The game creates a compelling world that engages the public on serious public health topics". The game series has been praised by the Centers for Disease Control and Prevention who said "it uses a non-traditional route to raise public awareness on epidemiology, disease transmission, and diseases/pandemic information. The developer has said that the game was inspired by Pandemic 2, a browser-based Flash game released in 2008 by Dark Realm Studios. However, there is a time pressure to complete the game before humans, the opponent, develop a cure for the plague. The player must infect and kill the whole world population by evolving the plague and adapting to various environments.
the player controls a plague which has infected patient zero. The core game of Plague Inc: Evolved is the same as Plague Inc. The user interface was optimized for console and PC. Gameplay screenshot of Plague Inc: Evolved showing a map of the world, with infected countries in red.
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